Publications

Fox E.F., Lamb M.C*., Mellentine S.Q*. and T.L. Tootle. (2020) Prostaglandins regulate invasive, collective border cell migration. MBoC. 15: 1584-1594. doi:10.1091/mbc.E19-10-0578

Lamb M.C., Anliker K.K., and T.L. Tootle. (2020) Fascin regulates protrusions and delamination to mediate invasive, collective cell migration in vivo. Developmental Dynamics. 249: 961-982. doi:10.1002/dvdy.186

FitzSimons M., Beauchemin , Kelpsch D., Lamb M., Tootle, T.L., and Yin, V. (2020) Cardiac injury modulates critical components of prostaglandin E2 signaling during zebrafish heart regeneration. Scientific Reports. 10: 3095. doi:10.1038/s41598-020-59868-6

Duan T., Green N.M., Tootle, T.L., and P Geyer. (2020). Nuclear architecture in Drosophila female GSCs. Current Opinion in Insect Science. Invited Review. 37: 30-38. doi: 10.1016/j.cois.2019.11.007

Palacios V., Kimble G.C., Tootle T.L., and M Buszczak. (submitted) Importin-9 regulates chromosome segregation and packaging in Drosophila germ cells. BioRxiv: https://doi.org/10.1101/2020.02.10.94232

Tootle T.L., Hoffmann D., Allen A., Spracklen A., Groen C., and D Kelpsch. (2019) Mini-course based undergraduate research experience: Impact on student understanding of STEM research and interest in STEM programs. Journal of College Science Teaching. 48:44-54

Wineland D*, Kelpsch D*, Tootle TL. (2018). Multiple pools of nuclear actin. The Anatomical Record. 301(12):2014-2036.

Kelpsch D, Tootle TL. (2018). Nuclear actin: from discovery to function. The Anatomical Record. 301(12):1999-2013

Article about the lab:

2017. Understanding development and disease: prostaglandins coordinate actin cytoskeletal remodeling.  Research Features 110: 26-29.

Jayo A, Malboubi M, Antoku S, Chang W, Ortiz-Zapater E, Groen C, Pfisterer K, Tootle T, Charras G, Gundersen G.G., Parsons M. 2016. Fascin Regulates Nuclear Movement and Deformation in Migrating Cells. Dev. Cell. 38:371-383.

Kelpsch DJ, Groen CM*, Fagan TN*, Sudhir S, Tootle TL. 2016. Fascin regulates nuclear actin during Drosophila oogenesis. MBoC. 27:2965-297.

Spracklen AJ, Tootle TL. 2015. Drosophila – a model for studying prostaglandin signaling. Bioactive Lipid Mediators: Current Reviews and Protocols. Springer Japan. Editors: Takehiko Yokomizo and Makoto Murakami.

Groen CM, Tootle TL. 2015. Visualization of Actin Cytoskeletal Dynamics in Fixed and Live Drosophila Egg Chambers. Drosophila oogenesis: Methods and Protocols. Springer Methods Mol Biol. Editors: Diana Bratu and Gerard McNeil. 1328:113-24.

Groen CM, Jayo A, Parsons M, Tootle TL. (2015) Prostaglandins regulate Fascin localization to the nucleus and function in nucleolar architecture. MBoC. 328:113-24.

Spracklen AJ, Fagan TN, Lovander KE, Tootle TL. (2014)  The pros and cons of common actin labeling tools for visualizing actin dynamics during Drosophila oogenesis. Dev. Biol. 393(2):209-26.

Spracklen AJ, Kelpsch DJ, Chen X, Spracklen CN, Tootle TL. (2014) Prostaglandins temporally regulate cytoplasmic actin bundle formation during Drosophila oogenesis. MBoC. 25(3):397-411.

Spracklen AJ, Tootle TL. (2013) The utility of stage-specific mid-to-late Drosophila follicle isolation. J Vis Exp. 2013 Dec 2;(82). doi: 10.3791/50493.

Tootle TL. (2013) Genetic insights into the in vivo functions of prostaglandin signaling. Int J Biochem Cell Biol. 45(8):1629-32.

Groen CM*, Spracklen AJ*, Fagan TN, Tootle TL (2012) Drosophila Fascin is a novel downstream target of prostaglandin signaling during actin remodeling. MBoC. 23(23)4567-4578.

Tootle TL, Williams D, Hubb A, Frederick R, Spradling A (2011) Drosophila eggshell production: identification of new genes and coordination by Pxt. PLoS One 6: e19943.

Tootle TL, Spradling AC (2008) Drosophila Pxt: a cyclooxygenase-like facilitator of follicle maturation. Development 135: 839-47